Risk factors for sporadic campylobacteriosis: A systematic review and meta-analysis

Campylobacter spp. is an important causative agent of diarrheal illness worldwide. The disease frequently associated with foodborne transmission, but other routes exposure are increasingly recognized. A systematic review and meta-analysis case-control studies were performed to determine the main risk factors sporadic campylobacteriosis. Suitable scientific articles published up March 2017 identified through a literature search subject methodological quality assessment. From each study, odds ratios (OR) as measures association extracted or calculated, well study characteristics such population, design, type model used factor categorization. Mixed-effects meta-analytical models adjusted by population appropriate data partitions. 4453 references, assessment stage was passed 71 focusing on eligible conducted between 1981 2012 provided 1336 ORs for meta-analysis. international travel (pooled OR=4.626), recent use gastric antacids OR=2.911), occupational animals/carcasses OR=3.022), food consumption (in particular raw undercooked eggs, poultry, beef, dairy) risks campylobacteriosis in mixed population. In child concerned environmental/animal transmission (e.g. drinking untreated water OR=3.261), recreational OR=3.156), farm/rural environment OR=3.128), contact farm animals OR=2.747), person-to-person OR=2.736) milk OR =2.603). results this highlight importance overlooked vehicles (environment, animal contact, vehicles) that should be explored dedicated studies.